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Senior Bioinformatician / Computational Biologist

Senior Bioinformatician / Computational Biologist

NateraUS Remote
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About the Role

Natera is seeking an experienced Senior Bioinformatician / Computational Biologist to join our innovative team. In this role, you'll leverage your expertise in NGS, quantitative biology, and methods development to advance our high-volume clinical diagnostic sequencing initiatives.

Key Responsibilities

  • Drive the development of novel NGS assays for clinical diagnostic applications as part of a dynamic, cross-disciplinary team of molecular and computational biologists
  • Design and implement robust analysis tools and pipelines for processing diagnostic assays across tumor, germline, and cell-free DNA samples
  • Collaborate closely with wet lab scientists to build, troubleshoot, and optimize complex, high-throughput NGS workflows involving diverse sample types and analytical targets
  • Partner with clinical staff to validate and successfully deploy assays into production environments
  • Contribute expertise throughout the entire process flow—from initial sequencing through validation and production implementation

Required Qualifications

  • PhD or MS in Bioinformatics, Computational Biology, Genomics, or related field
  • 4+ years of industry experience in clinical diagnostics or related field
  • Demonstrated expertise in DNA / RNA sequencing data analysis and interpretation
  • Proficiency working with public genomics data sources (HapMap, dbSNP, 1000 Genomes Project, TCGA, GTEx, UK Biobank)
  • Strong programming skills in Python and experience with scientific / bioinformatics libraries
  • Experience working in high-performance computing environments (Kubernetes, SGE, LSF, SLURM)
  • Practical knowledge of cloud computing platforms, particularly AWS or GCP
  • Familiarity with workflow orchestration languages such as WDL and Nextflow
  • What Sets You Apart

  • Experience in clinical diagnostics development and regulatory requirements
  • Track record of developing and deploying production-grade bioinformatics pipelines
  • Publications or patents in relevant fields
  • Strong communication skills and ability to collaborate across technical and non-technical teams
  • Join Natera and be part of a team that's transforming healthcare through cutting-edge genomic analysis.

    LI-TH1 #LI-Remote

    The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$116,200—$145,300 USD

    OUR OPPORTUNITY

    Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

    The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

    WHAT WE OFFER

    Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

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    Biologist • US Remote