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Staff / Sr. Staff / Principal I Engineer, Bioinformatics Software

Staff / Sr. Staff / Principal I Engineer, Bioinformatics Software

Pacific Biosciences of CaliforniaMenlo Park, California, USA
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Staff / Sr. Staff / Principal I Engineer Bioinformatics Software

We are seeking an experienced Bioinformatics Software Engineer specializing in C to join our Instrument Analysis team at PacBio (NASDAQ : PACB). In this role you will develop high-performance on-instrument software tools and algorithms that further our mission to advance scientific understanding through cutting-edge technologies. This position demands deep technical expertise in modern C development along with specialized knowledge of bioinformatics algorithms and statistical modeling.

Responsibilities :

  • Design and implement efficient bioinformatics algorithms for sequence analysis in modern C meeting performance-critical requirements.
  • Profile and optimize code to enhance memory efficiency and computational speed.
  • Develop clean well-documented APIs and libraries suitable for integration into broader software ecosystems.
  • Collaborate with team members sharing insights and best practices and fostering a culture of continuous improvement.
  • Maintain comprehensive and clear documentation covering software design implementation and optimization strategies.

Required Qualifications :

  • Masters or Ph.D. in Bioinformatics Computational Biology Computer Science or a related field.
  • 5 years of professional C development experience using modern standards.
  • Expert-level understanding of core bioinformatics concepts particularly in sequence analysis.
  • Proven experience developing complex algorithms with careful consideration of time and space complexity.
  • Proficiency with version control (Git) automated testing continuous integration and code review processes.
  • Experience with memory management multi-threading and system-level optimization.
  • Familiarity with common bioinformatics file formats (FASTA FASTQ SAM / BAM / CRAM VCF).
  • Demonstrated ability to debug complex software systems and identify performance bottlenecks.
  • Excellent interpersonal written and verbal communication skills.

    • Preferred Experience :

  • Knowledge of statistical methods and machine learning techniques in bioinformatics.
  • Familiarity with scientific visualization libraries and tools.
  • Contributions to open-source bioinformatics projects or tools.

    • This role is not eligible for visa sponsorship.

    Non-Field Based Employees are required to be onsite Monday-Thursday (Friday work from home). Depending on the role some employees may be required to be 100% onsite.

    You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.

    All listed tasks and responsibilities are deemed as essential functions to this position; however business conditions may require reasonable accommodations for additional tasks and responsibilities.

    All qualified applicants will receive consideration for employment without regard to race sex color religion national origin protected veteran status or on the basis of disability gender identity and sexual orientation.

    LI-Onsite

    Salary Range :

    170400.00 - $293900.00

    To all Staffing and Recruiting Agencies : Our Careers Site is only for individuals seeking a job at PacBio. Staffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles applications or resumes and any such submissions will be considered unsolicited. PacBio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias PacBio employees or any other company location. PacBio is not responsible for any fees related to unsolicited resumes / applications.

    All qualified applicants will receive consideration for employment without regard to race sex color religion national origin protected veteran status or on the basis of disability gender identity and sexual orientation.

    If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying you may contact us at or for assistance.

    Visit our following pages for more information on :

    FAQs

    Benefits

    Culture

    Equal Opportunity Employment

    Required Experience :

    Staff IC

    Key Skills

    Computer Science,Docker,Kubernetes,Python,VMware,C / C++,Go,System Architecture,gRPC,OS Kernels,Perl,Distributed Systems

    Employment Type : Full-Time

    Experience : years

    Vacancy : 1

    Monthly Salary Salary : 170400 - 293900

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    Software Engineer • Menlo Park, California, USA