RESEARCH INVESTIGATOR / ASSISTANT RESEARCH SCIENTIST / ASSOCIATE RESEARCH SCIENTIST / RESEARCH SCIENTIST

University of MichiganAnn Arbor, Michigan, US

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Summary

The Newman Lab, led by Dr. Erika A. Newman, MD, MBA and housed under the Section of Pediatric Surgery, is shifting the paradigm of pediatric neuroblastoma treatment. The Newman Lab is seeking a highly motivated and skilled Research Scientist to join a dynamic team focused on cutting-edge research in neuroblastoma, a pediatric cancer of the sympathetic nervous system. The successful candidate will contribute to ongoing projects investigating the molecular and cellular mechanisms driving neuroblastoma initiation, progression, and treatment resistance, and will play a key role in translational research efforts aimed at identifying novel therapeutic targets.

The academic rank for this position will be commensurate with the applicant's credentials.

Responsibilities

Develop, design, and conduct more complex experiments in line with a research plan and review results periodically with faculty member or senior research staff member
Perform molecular biology techniques (e.g., PCR, Western blotting, RNA-seq analysis, CRISPR / Cas9 editing)
Write and collaborate with other researchers on manuscripts, abstracts, technical reports and other publications of research findings
Contribute to grant writing and progress reports
Provide instruction and technical support to academic trainees in the lab
Direct day-to-day lab operations such as equipment maintenance and lab supply ordering
Coordinate the collection and analysis of data and the conduct of experimental procedures

Required Qualifications

Exceptional written and verbal communication skills and ability to interact with and build professional relationships with all individuals at all levels

Exceptional interpersonal skills and the ability to work independently and take initiative and within a team with minimal supervision

Strong organizational skills and ability to effectively manage numerous projects, simultaneously and in various stages of development, with a high attention to detail

Must have strong integrity, be highly proactive, have a high degree of problem-solving skills, be highly reliable, retain a sense of ownership and accountability for workload, be flexible and resilient, and possess expert follow-up skills

Proven ability to prioritize and manage multiple tasks with competing deadlines

Proven ability to write intramural and extramural grant proposals

Proven ability to teach and / or train students, junior laboratory personnel in laboratory techniques and / or protocols

Desired Qualifications

PhD in Cancer Biology or related field

More than 5 years of postdoctoral experience

Strong background in cancer research, preferably in pediatric oncology or neuroblastoma

Proficiency with mammalian cell culture, standard molecular / cellular biology techniques preferred

Ability to work with CRISPR and Cre-Lox models

Experience with identification and validation of drug targets, drug screening, target engagements and other standard cell biology techniques

Familiarity in DNA damage studies and has previous experience in DNA damage biomarkers

Familiarity with omics data (RNA-seq, ChIP-seq, proteomics) and analysis pipelines

Knowledge of immunotherapy, epigenetics, or tumor microenvironment research

Prior involvement in translational or drug discovery projects

Familiarity with University research administration, policies and procedures

Modes of Work

Positions that are eligible for hybrid or mobile / remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the

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Research • Ann Arbor, Michigan, US