Senior Information Systems Security Officer (ISSO)

Job Title : Senior Information Systems Security Officer (ISSO)

Location : Columbia, SC – 100% Onsite (Second interview onsite required)

Employment Type : Long-Term Contract, W2 only (no third-party candidates please)

Overview

We are seeking a Senior Information Systems Security Officer (ISSO) to lead security, risk, and compliance activities in support of enterprise-level cybersecurity initiatives. This role is fully onsite in Columbia, SC, and requires strong collaboration with leadership, business units, and vendors to ensure systems meet Federal, State, and industry security standards.

Key Responsibilities

• Direct the establishment, implementation, and enhancement of security and compliance efforts aligned with FISMA, NIST, HIPAA, CMS MARS-E, and other regulatory frameworks.
• Oversee development and maintenance of security documentation including System Security Plans (SSPs), Privacy Impact Assessments (PIAs), and Interconnection Security Agreements (ISAs).
• Perform detailed architectural reviews, risk assessments, and compliance audits of systems and vendor solutions.
• Support and guide cross-functional teams in designing secure, compliant solutions across infrastructure, applications, and cloud services.
• Serve as primary liaison for third-party audits, assessments, and regulatory reviews.
• Mentor and guide team members, promoting best practices in security and compliance.

Required Skills & Experience

Preferred Qualifications