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Associate Scientist, Bioinformatics

Associate Scientist, Bioinformatics

ZymeworksBellevue, WA, US
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Key Responsibilities

  • Works on the Translational Sciences Biomarkers and Bioinformatics team to support data analysis and infrastructure for discovery, preclinical and clinical biomarkers for novel therapeutics in development or early phase clinical trials.
  • Assists the team with the research, development and implementation of bioinformatics tools, and algorithms that facilitate the analysis of experimental and in-silico data.
  • Designs, conducts and / or validates statistical analysis of preclinical in vitro and in vivo experimental data, and assists scientists in making data-driven decisions.
  • Performs analysis of proteomic and genomic biomarker data from early phase clinical studies to assess safety, mechanism of action and efficacy of novel therapeutics.
  • Works with the scientists in Protein Engineering, Discovery Research, Therapeutics Research teams to gather requirements and specifications for bioinformatics methods and tools.
  • Implements bioinformatics methods for antibody discovery in conjunction with the software development group. Participates in the development of high-throughput and large dataset mining and analysis techniques.
  • Fosters effective and collaborative working relationships with fellow employees, management and external partners.

Education and Experience

  • MS or PhD in a scientific discipline (Bioinformatics, Mathematics, Computer Science or related field) and a minimum of 1-3 years' related experience or an equivalent combination of education and experience.

    • Skills and Abilities :

  • Strong skills in biological sequence analysis (e.g. experience with tumor target expression analysis TCGA, cBioportal, bioinformatics algorithm design). Experience in analysis of next generation sequencing data (eg oncoplots), tumor inhibition / repeated measures analysis.
  • Strong background in statistical analysis using R, SAS, Matlab or other statistical packages and familiarity with working in a high-performance environment.
  • Experience in implementing and validating informatics methods, workflows.
  • Effective software development skills in Python or any other programming language. Experience with building dashboards, performing biostatistics, preclinical / clinical trial biomarker dataset analysis in R studio, JMPPro, Spotfire to identify, evaluate prognostic / predictive biomarkers.
  • Experience with cancer genomics is a plus. Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team. Ability to establish and maintain effective working relationships.
  • Good organizational skills and the ability to work effectively in a high paced, fast changing environment. Results-oriented.
  • Excellent communication skills.

    • Total Rewards We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies.

    The US base salary range for this full-time position is $90, - $, + bonus + equity + benefits. Our salary ranges are determined by role, level, and location.

    The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience). Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes :

  • Industry leading vacation and paid time off
  • Excellent health and wellness benefits
  • Zymelife health and wellness benefits
  • Paid time off to volunteer in your community
  • Matching RRSP / K program
  • Employee Share Purchase Program
  • Employee Equity Program

    • All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

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    Associate Scientist • Bellevue, WA, US