VP, Supply Chain

VP, Supply Chain

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on In 2015, we pioneered a "moneyball for biotech" approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

Eidos Therapeutics, an affiliate within BridgeBio Pharma, is a commercial-stage biopharmaceutical company focused on Transthyretin Amyloid Cardiomyopathy (ATTR-CM).

What You'll Do

The Vice President of Global Supply Chain will be responsible for global end-to-end clinical supply chain activities related to managing supply of Investigational Product (IP) including packaging, labeling, distribution and demand forecasting for multiple clinical studies through all stages of clinical development. The role will also have responsibility for global end-to-end commercial supply chain activities, including the management of S&OP, Supply planning, Supplier (CMO, CPO, 3PL) management, inventory management, and partnership with Global Trade for Finished Good distribution. The role will partner closely with CMC / Manufacturing, Commercial, Clinical, and Quality Assurance teams and partner stakeholders to ensure timely and uninterrupted supply of clinical and commercial product. The individual must have the ability to manage global teams, experience in GxP industry, be an effective leader, and work efficiently in a fast-paced environment.

Responsibilities

• Manage a global team of supply chain professionals, responsible for both clinical and commercial end-to-end supply chain
• Manage all aspects of commercial supply chain, including Drug Substance and Drug Product Contract Manufacturing Organizations (CMOs), Packaging and Labeling activities with Contract Packaging organizations (CPOs), Finished Good receiving, put away, storage and distribution activities at Third Part Logistics Providers (3PLs)
• Coordinate logistics of material transfer for clinical and commercial drug substance, drug product and components to / from international CMOs / CPOs, managing exportation, applicable USDA / FDA licenses and permits, VAT recovery and customs brokers
• Own the global Sales & Operations Planning (S&OP) process for all commercial products, coordinating with global market access team for demand planning, finance team for financial planning and driving ownership of final supply plan to be communicated to global partners
• Own and actively manage the commercial supply plan, all commercial inventory, both in process and finished goods; manage shelf life and expiration
• Own and manage all serialization activities for commercial products globally
• Manage clinical packaging and labeling activities including label design, translation, production, distribution and inventory management
• Provide clinical demand signals, translate the total demand into a demand forecast over time based on a clinical protocol or study overview
• Prepare a clinical supply plan to support the demand, including determination of supply overage amounts, monitor inventory and provide regular inventory update to project teams
• Monitor clinical drug expiry / retest dating; initiate inventory release and re-supply, serving as the unblinded inventory manager
• Manage domestic and international distribution and logistics for clinical programs, including importing and exporting clinical supplies and developing distribution instructions with clinical supply vendors
• Support budget activities, including managing supplier contracts, PO generation and invoicing approvals for clinical and commercial purchases
• Work collaboratively with QA to manage supply chain activities such as batch release, final release, temperature excursions and to support the investigation of any deviations in a timely manner
• Work with CMC as a liaison to clinical operations and also on the evaluation of new CMOs or CPOs for commercial supply chain
• Work with Global Trade & Distribution and global Finance teams to manage global 3PLs, ensuring quality Finished Good inventory management, distribution and logistics, sales and revenue reporting
• Generate and maintain global SOPs in Veeva QMS and ensure updates and compliance with industry standards
• Develop and maintain strong internal cross-functional collaboration with stakeholders, such as CMC, Clinical Operations, Market Access, Finance, Quality, and Regulatory Affairs

Where You'll Work

This is a hybrid role and requires in-office collaboration 2-3x per week in our San Francisco Office.

Who You Are

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

Financial Benefits :

Health & Wellbeing :

Skill Development & Career Paths :