Director, Product Portfolio Strategy & Financial Performance

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Current Need

The Director of Product Portfolio Strategy & Financial Performance leads strategic, analytically-driven initiatives to enhance product performance, optimize investment allocation, and strengthen financial outcomes across assigned segments of McKesson’s digital and technology portfolio. This role partners closely with the VP of TPPPO and cross-functional leaders to evaluate product-level and portfolio-level economics, analyze and assess investment opportunities, and guide data-informed decision making. The Director collaborates deeply with business unit leaders to align priorities, analyze tradeoffs, and automate insights that maximize financial return and long-term value creation.

Key Responsibilities

Segment Portfolio Strategy & Execution

• Supports the VP in developing and executing analytically grounded cross-portfolio optimization strategies focused on specific market or product segments.
• Manages the multiyear financial and performance roadmap for assigned segments, including revenue, margin, cost optimization, and investment targets.
• Works with segment leadership to identify cross-product financial synergies, cost efficiencies, and opportunities for value expansion.
• Oversees segment-level KPIs such as revenue growth, profitability, adoption, retention, CAC / LTV, and ROI—developed jointly with business unit partners.
• Provides financial and data-driven recommendations for segment portfolio evolution based on market dynamics, product performance trends, and emerging financial signals.
• Communicates portfolio strategy and financial insights effectively to senior leadership and business unit executives.
• Partners with the Portfolio Management team to generate holistic assessments across customer sentiment, product opportunities and financial modeling to maximize digital product investments.

Digital Portfolio Management & Optimization

Cross-Functional Collaboration

Team Management

Technical & Analytical Expertise

Minimum Requirements

Degree or equivalent experience. Typically requires 12+ years of professional experience and 4+ years of management experience.

Critical Skills

Specialized Knowledge / Skills

Working Conditions

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$147,700 - $246,100

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!

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