Scientist, In Vivo Discovery

We are seeking a scientific contributor to lead and execute in vivo studies using novel LNP formulations designed to cross the BBB and target cells within the brain. This role will spearhead our CNS program and would be responsible for designing and executing in vivo studies using rodent models as well as downstream bioanalytic methods. The candidate would have the opportunity to work in a collaboration-oriented role in which they would coordinate with other teams plan and run animal studies with a cross-functional group of scientists and support the growth and career development of junior scientists. The ideal candidate is a life sciences major with strong in-vivo and ex-vivo analytic techniques who is excited by the idea of being a core participant in building an early startup and guiding the scientific vision of the company. They would be engaged in science and driven by our mission to create therapies that help people in ways that are currently impossible.

Key Responsibilities

• Design plan and execute in vivo experiments to support LNP based targeted delivery across the blood brain barrier through systemic administration
• Develop bioanalytical assays (cell-based flow cytometry ELISA biomedical imaging) to assess the delivery efficiency of RNA cargo in rodent tissue to facilitate development of neuroscience focused therapeutics pipeline
• Conduct studies in small animals models for brain characterization biodistribution (qualitative / quantitative) disease model development efficacy and toxicity assessment
• Contribute to patent applications related to the neuroscience program
• Perform CRO outreach including experimental planning work coordination and data interpretation for neuroscience program
• Support technology transfer to Industry Partners
• Foster collaborative relationships across the team and company and engage in a positive and exciting work environment
• Contribute to hiring training and collaborating with scientists (as needed) to support assessment of efficacy in relevant in vivo models
• Plan and coordinate animal studies with formulations team members
• Author technical documents including SOPs for analytical methods maintain diligent records and demonstrate proficiency in scientific communication
• Support high-quality documentations to support regulatory filings

Qualifications :

Minimum Qualifications :

Preferred Qualifications :

Additional Information :

What We Offer :

At our RNA Venture we aim to outmatch the typical benefits you might see in an early startup. We offer :

Remote Work : Employment Type :

Full-time

Key Skills

Laboratory Experience,Immunoassays,Machine Learning,Biochemistry,Assays,Research Experience,Spectroscopy,Research & Development,cGMP,Cell Culture,Molecular Biology,Data Analysis Skills

Experience : years

Vacancy : 1