Senior / Principal Business Manager- Translational Medicine

The Position

We advance science so that we all have more time with the people we love.

The Senior / Principal Business Manager will serve as a strategic advisor and thought partner to senior leadership within the gRED Translational Medicine organization. This individual will play a critical role in driving cross-functional alignment, enabling business planning and operational excellence, and ensuring the successful execution of strategic priorities. The role requires strong business acumen, systems thinking, and the ability to influence and partner across multiple levels and functions. The Business Manager also enables leadership team effectiveness by shaping agendas, connecting strategic dots, and anticipating organizational needs. With a strong grasp of the enterprise landscape, the Senior Business Manager proactively connects strategic priorities to execution, facilitates sound decision-making, and identifies opportunities to strengthen how the organization operates, collaborates, and delivers impact.

The Opportunity :

As a valuable member on the Translational Medicine team you will be :

• Serving as a strategic thought partner to senior functional leaders (Director and Vice President level), providing insights and driving aligned decision-making in support of organizational goals.
• Leading short- and long-term business planning efforts, including annual planning cycles, resource allocation, budget forecasting, and functional goal setting.
• Driving leadership team operating rhythm, ensuring effective prioritization, focus, and delivery on strategic objectives.
• Anticipating emerging needs, risks, and opportunities across the organization and proactively frames options for leadership consideration.
• Facilitating effective leadership and project team operations—designing and executing agendas, preparing briefing materials, and ensuring clarity of decisions, follow-ups, and outcomes.
• Connecting the dots across initiatives and stakeholders, identifying interdependencies and proactively addressing risks and opportunities.
• Synthesizing data and perspectives to support informed decision-making, including preparing pre-reads, strategic recommendations, and decision frameworks for leadership discussions.
• Driving planning and execution of strategic initiatives and change efforts that support the function’s success and alignment with gRED and enterprise priorities.
• Advising on and contributing to solutions for complex challenges, offering structure, process, and creative thinking to move initiatives forward.
• Supporting key people and culture activities—such as functional offsites, recognition programs, and engagement initiatives—helping to foster a high-performance, inclusive, and purpose-driven environment.
• Acting as a connector across teams, promoting collaboration, shared accountability, and alignment toward common goals.
• Supporting communication strategies to ensure transparency, clarity, and engagement across stakeholders and organizational levels.
• Bringing a strong enterprise mindset, continuously linking functional goals to broader strategic context and organizational objectives.

Who You Are

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California for Senior Business Manager is $144,000- $267,400 and Principal Business Manager is $156,500-$290,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company\'s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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