Sr. Scientist - LNP Formulation

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical / biopharmaceutical company, all while maintaining full-time benefits.

Key responsibilities :

• Manufacture small and large scale LNP formulations including production, purification and analysis of LNPs using established protocols.
• Optimize formulation processes, such as mixing rate and purification conditions to improve yields and scalability of formulation.
• Troubleshoot low-yield processes and compositions to achieve formulation targets (, composition design to enable specific delivery outcomes).
• Troubleshoot challenges arise during protocol execution and identify opportunities for protocol and / or process improvement.
• Meet established deadlines.
• Maintain clear and complete ELN-based experimental records.
• Follow SOPs to generate and maintain thorough and accurate documentation.
• Collect data systematically, interpret and synthesize results into cohesive conclusions.
• Generate custom lipid-based formulations and targeting molecules to optimize LNP delivery for various tissues.