Scientist, Oligonucleotide Chemistry

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

Job Function :

Discovery & Pre-Clinical / Clinical Development

Job Sub Function : Chemical Research

Job Category :

Scientific / Technology

All Job Posting Locations :

San Diego California United States of America

Job Description :

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for Scientist Oligonucleotide Chemistry in San Diego CA.

Purpose : RNA Therapeutics and Delivery is embedded in Cell & Genetic Medicines an organization within Therapeutics Discovery where we are committed to the development of high-quality drug candidates in the Oligonucleotide Therapeutics space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking a portfolio approach and deep scientific knowledge and expertise in several fields including oligonucleotide chemistry bioconjugation chemistry nanotechnology cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers growth opportunity within a dynamic and science driven organization.

You will be responsible for :

• Perform solid phase synthesis purification and analysis of oligonucleotides and bioconjugates in a team environment.
• Support and trouble-shoot process development efforts for synthesis and characterization of oligonucleotides and their bioconjugates with higher throughput and automation.
• In collaboration with the team support oligonucleotide analytical efforts optimization and design for de-risked tissue-specific delivery.
• Collect document and evaluate experimental data and communicate scientific findings as verbal presentations and written reports.

Qualifications / Requirements :

Skills / Experience :

Required :

Preferred Qualifications :

The expected pay range for this position is $76000 to $121000

The Company maintains highly competitive performance-based compensation programs. Under current guidelines this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporations performance over a calendar / performance year. Bonuses are awarded at the Companys discretion on an individual basis.

Vacation 120 hours per calendar year

For additional general information on company benefits please go to : job posting is anticipated to close on December 11 2025. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please contact us via or contact AskGS to be directed to your accommodation resource.

Required Skills : Preferred Skills :

Analytical Reasoning Chemistry Data Analysis Data Reporting Drug Discovery Development Execution Focus Innovation Interdisciplinary Work Laboratory Experiments Process Oriented Quantitative Research Research Ethics Research Informatics Scientific Evaluation Scientific Research Technical Writing Technologically Savvy

The anticipated base pay range for this position is :

$76000 to $121000

Additional Description for Pay Transparency :

Subject to the terms of their respective plans employees and / or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs : medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance. Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Companys long-term incentive program. Subject to the terms of their respective policies and date of hire Employees are eligible for the following time off benefits : Vacation 120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year Holiday pay including Floating Holidays 13 days per calendar year Work Personal and Family Time - up to 40 hours per calendar year Parental Leave 480 hours within one year of the birth / adoption / foster care of a child Condolence Leave 30 days for an immediate family member : 5 days for an extended family member Caregiver Leave 10 days Volunteer Leave 4 days Military Spouse Time-Off 80 hours Additional information can be found through the link below.

Key Skills

Laboratory Experience,Immunoassays,Machine Learning,Biochemistry,Assays,Research Experience,Spectroscopy,Research & Development,cGMP,Cell Culture,Molecular Biology,Data Analysis Skills

Employment Type : Full-Time

Experience : years

Vacancy : 1

Monthly Salary Salary : 76000 - 121000