Senior Clinical Program Manager

Senior Clinical Program Manager

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

This is a unique opportunity for a Senior Clinical Program Manager (Sr. CPM). You will be responsible for providing strategic clinical operations leadership across a portfolio of trials, ensuring operational excellence and full accountability for trial execution. This position will report into the Associate Director, Clinical Operations.

Responsibilities

• Apply extensive industry experience and exercise wide latitude in determining objective and approve significantly complex, multi-discipline or function-wide assignments.
• Oversee the execution of the Clinical Study Execution Team (CSET) meetings and provide strategic context and clarity where needed.
• Oversee operational delivery across multiple study(ies).
• Lead multiple departmental or interdepartmental strategic initiatives as it relates to broader organizational topics. Known as the subject matter expert and point of contact for specific study trial(s).
• Ensure inspection readiness and quality compliance.
• Provide operational input into protocol design, study documents, and regulatory submissions.
• Ensure alignment and consistency across trial teams, vendors, and systems.
• Oversee the development of RFPs and selection of CROs / vendors.
• Trian CROs, vendors, investigators, and study coordinators, as well as cross-functional partners on study requirements.
• Oversee vendor management develop strong collaborative relationship with internal and external stakeholders.
• Review, approve, and manage study-level budget and drive cost control.
• Identify resourcing needs and lead the recruiting and hiring process, as well as make the decision for hiring.
• Mentor and train Clinical Program Managers (CPMs), Clinical Trial Managers (CTMs), Clinical Trial Management Associates (CTMAs), and Clinical Trial Assistants (CTAs).
• Manage individual contributors including performance management.
• Conduct risk management, contingency, and scenario planning.
• Participate in other Clinical Operations activities as appropriate.

Required Skills, Experience and Education

Preferred Skills