Sr. Manager, Marketing and Corporate Strategy

The Senior Manager, Marketing and Corporate Strategy will play a pivotal role in shaping the commercial direction of Lexeo's leading cardiac programs and organization. With multiple catalysts expected in 2026, it is crucial to define and refine commercial assumptions as lead programs advance, and to support the expansion of Lexeo's growing commercial organization and capabilities. This role focuses on characterizing the current and evolving landscape in gene therapy and rare cardiovascular disease, particularly Friedreich ataxia (FA) cardiomyopathy and arrhythmogenic cardiomyopathy (ACM). Additionally, this role will encompass corporate strategy responsibilities, supporting commercial development, pipeline strategy and prioritization and other high-impact projects with senior executives as Lexeo evolves.

Primary Responsibilities

• Conduct market research, including primary and secondary research, to outline market dynamics in FA, ACM and across other genetic medicine targets, such as unmet needs, key stakeholders, existing treatment paradigms, and competition, focusing on the U.S. and key international markets.
• Leverage research and insights to define how the company's gene therapy candidates may meet unmet needs and impact future treatment paradigms.
• Collaborate closely with clinical colleagues to understand target product profiles and identify patient populations eligible for treatment.
• Identify and map key stakeholders involved in the treatment of FA and ACM, as well as those involved in the potential administration of cardiac gene therapy.
• Compile information on current treatment costs, payer perspectives, patient coverage types, treatment expenditure, and other medical costs.
• Analyze commercially available gene therapies in key markets, identifying successful constructs that maximize patient access or enable value-based reimbursement.
• Outline recommended investments and timelines for commercial scale-up over the next three years, including necessary commercial capabilities and colleagues.
• Develop and implement operational plans to ensure the efficient execution of commercial and corporate strategies.
• Support senior executives and business development colleagues with corporate strategy initiatives such as pipeline prioritization and development strategy optimization and other organizational planning
• Monitor and evaluate the performance of commercial initiatives, providing insights and recommendations for continuous improvement.
• Advance Lexeo objectives commercially, including support for corporate communications, media awareness, and internal employee initiatives that increase knowledge and understanding of lead programs and strategies
• Work closely with colleagues in Clinical Development, Medical Affairs, Program Management, and other relevant departments to ensure cohesive strategy execution.
• Report to the Senior Director of Commercial Marketing, regularly updating on project progress and strategic recommendations.
• Present findings and strategic recommendations to company leadership, facilitating informed decision-making.

Required Skills & Qualifications

$140,000 - $180,000 a year

About Lexeo

LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO's foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medicine and the University of California, San Diego. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases and APOE4-associated Alzheimer's disease and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing, and commercialization

Our work culture is a hybrid model with 2 days / week in the New York City office and days working from home.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.