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PRN Principal Investigator
PRN Principal InvestigatorDSD Recruitment • Plano, TX, US
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PRN Principal Investigator

PRN Principal Investigator

DSD Recruitment • Plano, TX, US
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Job Description

The Principal Investigator is responsible for the overall conduct of clinical trials at the site, ensuring adherence to FDA, ICH-GCP, and IRB regulations. The PI provides medical oversight, reviews study documents, evaluates participant eligibility, ensures safety, and collaborates with the study team to maintain high-quality research data and patient care.

Key Responsibilities

Clinical Oversight & Patient Safety

  • Provide medical and scientific oversight for assigned clinical trials.
  • Conduct or oversee physical exams, medical evaluations, and eligibility assessments for study participants.
  • Ensure participant safety through timely assessment and reporting of adverse events (AEs) and serious adverse events (SAEs).

Protocol & Compliance Management

  • Review and approve study protocols, informed consent forms, and regulatory documents.
  • Ensure all study procedures are performed in accordance with the protocol, GCP guidelines, and IRB requirements.
  • Maintain accurate and complete documentation in the Investigator Site File (ISF).
  • Participate in monitoring visits, audits, site qualification visits (SQVs), and site initiation visits (SIVs) as needed.
  • Collaboration & Communication

  • Work collaboratively with the Site Director, Study Coordinators, and Sub-Investigators.
  • Provide guidance to the research team regarding medical decisions related to protocol conduct.
  • Attend team meetings and training sessions related to ongoing or upcoming studies, as needed.
  • Regulatory Responsibilities

  • Maintain current credentials, medical license, and GCP certification.
  • Ensure the site is always prepared for sponsor or regulatory authority audits.
  • Qualifications

    Required :

  • MD or DO with an active, unrestricted Texas medical license.
  • Board certification or board eligibility in any specialty.
  • Strong interest in clinical research and regulatory compliance.
  • Excellent documentation, communication, and organizational skills.
  • Availability for PRN support (protocol review, eligibility decisions, safety oversight).
  • Preferred :

  • Previous experience as a Principal Investigator (PI) or Sub-Investigator.
  • Prior clinical research experience (GCP training can be provided).
  • Experience reviewing study protocols or managing patient care in a clinical setting.
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    Principal Investigator • Plano, TX, US

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